CIRCIO HOLDING ASA CRNA NON-REGULATORY PRESS RELEASES

Circio hosts live webcast today 28 May 2026 at 10:00 am CEST

28. May 2026 kl. 07:00

* Circio presented an extensive circVec data package in an oral and a poster presentation at the ASGCT 2026 Annual Meeting * The warrant program exercise period between 26 May -- 9 June offers the opportunity for warrant holders to subscribe for Circio shares at a discount to the VWAP from the warrant pricing period * CEO Dr. Erik D Wiklund will summarize the ASGCT presentation, provide an overview of the warrant process and secured underwriting, and the planned use of proceeds for the warrant funds received

Oslo, Norway, 28 May 2026 -- Circio Holding ASA (OSE: CRNA), a biotechnology company developing novel circular RNA expression technology for gene and cell therapy, will host a live webcast in Norwegian at 10:00am CEST today, Thursday 28 May 2026. The webcast presentation is attached to this press release.

In the webcast, CEO Dr. Erik D Wiklund will summarize the recent oral and poster presentations given at the ASGCT Annual Meeting in Boston 11-15 May 2026 where Circio presented an extensive data package showcasing the latest data package on its circVec circular RNA technology platform. The webcast will also include practical information and timelines relating to the warrant program with exercise period from 26 May to 9 June, including the structure of the secured NOK 150 million underwriting and the planned use of proceeds for warrant funds received.

The webcast will be held in Norwegian. Questions can be submitted in advance by email to Erik D Wiklund: erik.wiklund@circio.com or directly in the live webcast.

Time: 10:00 CEST on Thursday 28 May 2026

Click here to access Teams webcast (https://teams.microsoft.com/meet/332542909160846?p=A6gvhzCTeBuLqLxpH3) Meeting ID: 332 542 909 160 846 Passcode: kH6xK9CP

A recording of the webcast will be made available on the Circio webpage (http://www.circio.com/) and the presentation materials are attached hereto.

For further information, please contact: Erik Digman Wiklund, CEO Phone: +47 413 33 536 Email: erik.wiklund@circio.com

Lubor Gaal, CFO Phone: +34 683 34 3811 Email: lubor.gaal@circio.com

About Circio Building circular RNA expression systems for enhanced gene and cell therapies

Circio Holding ASA is a biotechnology company developing novel circular RNA expression technology for gene and cell therapy.

Circio has established a unique circular RNA (circRNA) vector expression technology for next generation RNA, DNA and viral therapeutics. The proprietary circVec platform is based on a modular genetic construct designed for efficient biogenesis of multifunctional circRNA inside target cells. The circVec platform has applications in multiple therapeutic settings, including genetic medicine, cell therapy and chronic disease. It has demonstrated 75-fold increased RNA half-life and up to 50-fold enhanced protein expression vs. conventional mRNA-based viral and non-viral vector systems, with the potential to become a new gold-standard gene expression technology. The circVec R&D activities are being conducted by the wholly owned subsidiary Circio AB in Stockholm, Sweden.